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INTRODUCTION

IMMUNOLOGY

BACTERIOLOGY

VIROLOGY

PARASITOLOGY

MYCOLOGY

INFECTIOUS DISEASE

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PART THREE: VIROLOGY

Virology is the study of viruses, complexes of nucleic acids and proteins that have the capacity for replication in animal, plant and bacterial cells. To replicate themselves, viruses usurp functions of the host cells on which they are parasites.  The viral parasite causes changes in the cell, particularly its antigenicity; moreover, directing the host cell's metabolism to the production of new virus particles may cause cellular death. Virally-induced cell death, changes in antigenicity and the response of the host to the presence of the virus leads to the manifestations of viral disease.

Viruses come in two basic types, those that have a genome of DNA and those that have a genome of RNA.

 

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Virology Quiz I

Virology Quiz II

 

VIRUS GLOSSARY

Logo image Jeffrey Nelson, Rush University, Chicago, Illinois  and The MicrobeLibrary

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BACTERIOLOGY    IMMUNOLOGY    VIROLOGY    PARASITOLOGY    MYCOLOGY

  
CHAPTER ONE
Definitions, Classification, Morphology and Chemistry
An introduction to viruses, their nature, structure and classification    
 
CHAPTER TWO
Virus replication Strategies
Principal events involved in replication: Adsorption, penetration, uncoating nucleic acid and protein synthesis, assembly, maturation and release    
CHAPTER THREE
DNA Virus Replication Strategies 
Replicative strategies employed by animal DNA viruses.  Identification of virus prototypes associated with different DNA virus replication schemes    
CHAPTER FOUR
RNA Virus Replication Strategies 
Replicative strategies employed by animal RNA viruses. Identification of virus prototypes associated with different RNA virus replication schemes    

 

 

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CHAPTER FIVE
Viral Genetics 
Introduction to animal virus genetics

 

   
CHAPTER SIX
Oncogenic Viruses
Viruses that cause cancer and the mechanisms by which they do so: DNA cancer viruses (polyoma, herpes, papilloma, hepatitis, adenovirus). RNA cancer viruses (retroviruses)    
CHAPTER SEVEN
Human Immunodeficiency Virus
The biology of the virus that causes AIDS
   
CHAPTER EIGHT
Molecular Approaches to the Development of Viral Vaccines
History of vaccines especially smallpox and polio. New methods: subunit vaccines, anti-idiotype and DNA vaccines    
CHAPTER NINE
Viral Chemotherapy 
Drugs that have been used against viruses: Nucleoside analogs, reverse transcriptase inhibitors, protease inhibitors      
CHAPTER TEN - PART ONE
PICORNAVIRUSES: ENTEROVIRUSES

CHAPTER TEN - PART TWO
PICORNAVIRUSES: RHINOVIRUSES

CHAPTER TEN - PART THREE
REPLICATION OF POLIO AND OTHER PICORNAVIRUSES

Picornaviruses: Small RNA viruses that cause infections of the alimentary tract including polio (enteroviruses) and of the upper respiratory tract (rhinoviruses)     

CHAPTER ELEVEN
Herpesvirus
The structure of herpes viruses. The diseases caused by herpes simplex types 1 and 2, cytomegalovirus, varicella-zoster virus, Epstein-Barr virus and other herpes types.     
CHAPTER TWELVE
Virus-Host InteractionS
Host specific and nonspecific defense mechanisms involved in resistance to and recovery from virus infections. Role of interferon in viral infections. Mechanisms by which interferon exerts its antiviral activity. Contributions of various host defense mechanisms in viral infections    
CHAPTER THIRTEEN
Influenza virus
Influenza virus structure and properties. Viral pathogenesis and disease, genetics, epidemiology, prevention and treatment    

  

CHAPTER FOURTEEN
Mumps, Measles 
Structure and properties of measles and mumps viruses. Viral pathogenesis and disease, epidemiology, prevention and
treatment
   
CHAPTER FIFTEEN
Rubella
Structure and properties of rubella virus. German Measles pathogenesis and disease, epidemiology, prevention and treatment
CHAPTER SIXTEEN
Parainfluenza, Respiratory SyncYtial and Adeno Virus

 

Viruses that cause respiratory disease    
CHAPTER SEVENTEEN
Rotaviruses and Other Agents of Viral Gastroenteritis
Viruses that cause alimentary tract infections    
CHAPTER EIGHTEEN
Hepatitis Viruses 
The structure and replication of hepatitis A to E    
CHAPTER NINETEEN - PART ONE
HEPATITIS
A AND E (Infectious and enteric non-A, non- B)

CHAPTER NINETEEN - PART TWO
HEPATITIS B, C, D AND G (Serum hepatitis, non A, non-B hepatitis and Delta Antigen)

The diseases that are caused by the hepatitis viruses    
CHAPTER TWENTY
Rabies
 
Rhabdoviruses and the disease of rabies    
CHAPTER TWENTY ONE
Arboviruses

 

CHAPTER TWENTY TWO
VIRAL DISEASES TRANSMITTED BY VERTEBRATES

Arbovirus encephalitis, febrile and hemorrhagic disease. Rodent borne hemorrhagic fever, hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome. Other filovirus-associated hemorrhagic fevers    
CHAPTER TWENTY THREE
Conventional and Unconventional Agents (Slow Viral Diseases) 
Slow viral diseases of the
central nervous system.
Progressive multifocal
leukoencephalopathy.
Sub-acute sclerosing panencephalitis (measles virus)
Prion diseases: Kuru, 
Creutzfeld-Jakob disease
   
CHAPTER TWENTY FOUR
Bacteriophage
Structure of bacteriophage. The infectious process and the lytic multiplication cycle. The lysogenic cycle and its regulation.  
CHAPTER TWENTY FIVE
CORONAVIRUSES - COLDS AND SARS
The viruses that cause about one third of common colds and the newly described severe acute respiratory syndrome  
CHAPTER TWENTY SIX
PARVOVIRUSES AND FIFTH DISEASE
Childhood rash disease

BACTERIOLOGY    IMMUNOLOGY    VIROLOGY    PARASITOLOGY    MYCOLOGY