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Office: 803 733 3288
Fax: 803 733 3192
E-mail:
afox
@med.sc.edu
Department of Pathology and Microbiology, University
of South Carolina School of Medicine, Columbia, SC 29208
Dr
Fox's curriculum vitae is
here (PDF file) |
Recent Publications
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Our research interest relates to biodefense and
homeland security encompassing proteomics. We are developing a novel anthrax
vaccine funded by NIH. A carbohydrate was discovered, by our group, which
surrounds the spore of Bacillus anthracis that was subsequently shown to be a
component of two glycoproteins. These glycoproteins are serving as the focus for
our vaccine studies. The spore is the infective agent and thus the earliest
stage of the disease process is being targeted. The current US anthrax vaccine
for human use involves a later stage of the disease, when the dormant spore has
germinated into a vegetative form, and produced a life-threatening lethal toxin.
Other interests are in the area of diagnostics relating to biodetection (rapid
detection of a biological warfare attack) and forensics (source verification,
e.g. the Amerithrax attacks on the US postal service). Dr. Fox is the
Editor-in-Chief of the Journal of Microbiological Methods, joint-Editor-in-Chief
of Molecular and Cellular Probes and is on the Editorial board of the Journal of
Clinical Microbiology. |
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Learn about the research of other faculty
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